This issue brief reviews the evidence-base to assess the impact of HR 5376 on drug innovation and patient health. A large academic literature estimates the effect of future drug revenues on R&D spending and finds that on average that a 1 percent reduction in revenue leads to a 1.5 percent reduction in R&D activity. We find that HR 5376 will reduce revenues by 12.0 percent through 2039 and therefore that the evidence base predicts that R&D spending will fall about 18.5 percent, amounting to $663 billion. We find that this cut in R&D activity leads to 135 fewer new drugs. This drop in new drugs is predicted to generate a loss of 331.5 million life years in the US, 31 times as large as the 10.7 million life years lost from COVID-19 in the US to date. These estimated effects on the number of new drugs brought to market are 27 times larger than projected by CBO, which finds only 5 drugs will be lost through 2039, equaling a 0.63 percent reduction. Click here to read the full paper.
Issue Brief: The Impact of HR 5376 on Biopharmaceutical Innovation and Patient Health
by jmanor | Nov 30, 2021 | White Papers | 33,590 comments
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Muscular endurance is the ability of a muscle or group of muscles to sustain repeated contractions against resistance for an extended period.
The greater your muscular endurance, the more reps you can do of a particular exercise.
It is just one of the components of muscular fitness,
along with muscular strength, flexibility, and power. In strength
training, muscular endurance refers to the number of repetitions of a
single exercise you can do without needing to stop and rest.
Examples include how many times you can do a full squat, a sit-up,
or a biceps curl with a light to moderate weight before breaking form.
Muscular endurance is muscle-specific. In other words, you may have more endurance with squats than with biceps curls.
It all depends on which muscles you train. The type of muscular endurance
used during cardiovascular fitness activities such as
running, swimming, or cycling is usually called cardiovascular
endurance or cardiorespiratory endurance and is different from the strength-training definition.
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