Issue Brief: The Impact of HR 5376 on Biopharmaceutical Innovation and Patient Health

by | Nov 30, 2021 | White Papers | 4,340 comments

This issue brief reviews the evidence-base to assess the impact of HR 5376 on drug innovation and patient health. A large academic literature estimates the effect of future drug revenues on R&D spending and finds that on average that a 1 percent reduction in revenue leads to a 1.5 percent reduction in R&D activity. We find that HR 5376 will reduce revenues by 12.0 percent through 2039 and therefore that the evidence base predicts that R&D spending will fall about 18.5 percent, amounting to $663 billion. We find that this cut in R&D activity leads to 135 fewer new drugs. This drop in new drugs is predicted to generate a loss of 331.5 million life years in the US, 31 times as large as the 10.7 million life years lost from COVID-19 in the US to date. These estimated effects on the number of new drugs brought to market are 27 times larger than projected by CBO, which finds only 5 drugs will be lost through 2039, equaling a 0.63 percent reduction. Click here to read the full paper.

4,340 Comments

← Older Comments
Newer Comments →
  1. Antwan on March 10, 2025 at 8:17 pm

    Hi there, I read your new stuff daily. Your humoristic style is witty,
    keep doing what you’re doing!

    my blog post :: BOKEP INDONESIA

  2. Ermelinda on March 10, 2025 at 8:31 pm

    Oh my goodness! Amazing article dude! Many thanks, However I
    am having difficulties with your RSS. I don’t know why I cannot subscribe to
    it. Is there anyone else having similar RSS issues? Anybody who knows the answer will you
    kindly respond? Thanks!!

    Feel free to surf to my site; best drugs

  3. Hazel on March 10, 2025 at 9:18 pm

    Today, while I was at work, my cousin stole my iphone and tested to see if it can survive a 40 foot drop, just so she can be a youtube sensation. My
    iPad is now broken and she has 83 views. I know this
    is completely off topic but I had to share
    it with someone!

    Review my web-site; big dick

  4. Ronald on March 10, 2025 at 10:30 pm

    What Can A Weekly Auto Locksmiths Luton Project Can Change Your Life Best Luton auto Locksmith

  5. Lasonya on March 10, 2025 at 11:20 pm

    Wow that was strange. I just wrote an really long comment
    but after I clicked submit my comment didn’t show up.
    Grrrr… well I’m not writing all that over again. Anyhow,
    just wanted to say wonderful blog!

    Here is my website – 울산출장안마

  6. Trista on March 11, 2025 at 2:38 am

    See What Auto Locksmiths Luton Tricks The Celebs Are Using auto locksmiths Luton

  7. Regena on March 11, 2025 at 2:44 am

    Auto Locksmiths Near Bedford Tools To Streamline Your Daily Life Auto Locksmiths Near Bedford Technique Every Person Needs To Be Able
    To auto locksmiths near bedford (Ariel)

  8. Sanford on March 11, 2025 at 2:53 am

    Nice respond in return of this query with genuine arguments and describing everything on the topic of
    that.

    Here is my web page: sex chịch nhau không che

  9. Nydia on March 11, 2025 at 3:17 am

    Guide To Replacement Lock For Composite Door: The Intermediate Guide In Replacement Lock For
    Composite Door replacement Lock for composite Door
    (intern.ee.aeust.edu.tw)

  10. Shawnee on March 11, 2025 at 5:28 am

    You’ll Never Guess This Gotogel’s Tricks gotogel

  11. cellucare on March 11, 2025 at 6:16 am

    CelluCare Blood Sugar Supplement is gaining popularity for its natural formula designed to regulate glucose levels. But does it really help? Some users experience improved energy and balanced sugar levels, while others don’t notice much change. Have you tried it? Did it help you maintain stable blood sugar, or did you see little to no results? Your review can help others decide.

  13. mitolyn usa website on March 11, 2025 at 6:33 am

    Mitolyn usa website claims to be an effective weight loss supplement that supports metabolism and fat burning. But is it really effective? Some users report great results, while others say they didn’t notice any changes. If you’ve tried it, did it help you lose weight, or was it a waste of time? Share your thoughts and let others know if Mitolyn is worth trying!

  14. Lindsay on March 11, 2025 at 6:47 am

    A Trip Back In Time How People Discussed Adhd Assessment Uk 20 Years Ago how to get a
    adhd assessment – Katherine –

  15. Laurene on March 11, 2025 at 6:50 am

    Write more, thats all I have to say. Literally,
    it seems as though you relied on the video to make your point.

    You obviously know what youre talking about, why throw away your intelligence
    on just posting videos to your site when you could be giving
    us something enlightening to read?

    My homepage Check Out Your URL

  16. Ezra on March 11, 2025 at 9:14 am

    10 Things You’ve Learned From Kindergarden That Will Aid You In Obtaining Buy Macaw Owning A Macaw

  17. Pedro on March 11, 2025 at 9:31 am

    What’s The Current Job Market For ADHD Women UK Professionals?
    adhd women uk (nagievonline.Com)

  19. Nicolas on March 11, 2025 at 10:48 am

    After I originally left a comment I seem to have clicked
    the -Notify me when new comments are added- checkbox and from now on each time a comment is added I recieve four emails with the same comment.

    Is there a means you are able to remove me from that service?

    Kudos!

    Stop by my web blog :: 출장마사지

  20. Athena on March 11, 2025 at 10:57 am

    Ten Reasons To Hate People Who Can’t Be Disproved How Much
    Does A Psychiatric Assessment Cost psychiatric Assessment liverpool

  21. Charla on March 11, 2025 at 11:04 am

    EPIK is a extremely competutive plan so meeting the minimum specifications does not assure you’ll acquiore a placement.

    my blog post; Misooda

  23. Daisy on March 11, 2025 at 12:43 pm

    You’ll Never Guess This Add Psychiatrist Near Me’s Benefits add Psychiatrist near me

  24. Mae on March 11, 2025 at 1:48 pm

    You’ll Never Guess This Keyrepair’s Tricks keyrepair

  27. Collin on March 11, 2025 at 3:26 pm

    Link exchange is nothing else except it is simply
    placing the other person’s web site link on your page at suitable place and other person will also do similar in support
    of you.

    my site :: BOKEP INDONESIA

  28. Luther on March 11, 2025 at 3:28 pm

    Hey there, You’ve done an incredible job.

    I will certainly digg it and personally suggest to my
    friends. I’m confident they will be benefited from this website.

    my web-site … ggbet303 link alternatif

  30. Lorrie on March 11, 2025 at 4:33 pm

    Hi to all, how is everything, I think every one is getting more
    from this website, and your views are pleasant designed for new viewers.

    Feel free to surf to my web site … singapore prize live draw

  31. live100plus on March 11, 2025 at 5:04 pm

    I appreciated your work very thanks بت

  35. Arnulfo on March 11, 2025 at 8:32 pm

    Situs Togel Terpercaya Tools To Make Your Daily
    Life Situs Togel Terpercaya Trick That Every Person Must Learn situs togel terpercaya

  36. Nam on March 11, 2025 at 8:50 pm

    This Is A Psychiatric Assessment Success Story You’ll Never Imagine psychiatry Uk assessment

  37. Sherryl on March 11, 2025 at 9:20 pm

    Incredible points. Outstanding arguments. Keep up the good spirit.

    Here is my web-site diyarbakır escort

  38. Leslie on March 11, 2025 at 10:23 pm

    15 Top Twitter Accounts To Learn More About Situs Gotogel Jackpot togel

  41. Porfirio on March 11, 2025 at 11:40 pm

    Psychiatrist Online Tools To Ease Your Daily Life Psychiatrist Online Trick
    Every Individual Should Know Psychiatrist Online

  43. Shane on March 11, 2025 at 11:41 pm

    Very soon this web site will be famous amid all blogging and site-building people, due
    to it’s fastidious articles

    Feel free to surf to my web page … BOKEP INDONESIA

  44. Kelley on March 12, 2025 at 1:34 am

    This site was… how do I say it? Relevant!!
    Finally I have found something which helped me.
    Appreciate it!

    my blog post: BOKEP INDONESIA

  45. Amelia on March 12, 2025 at 1:59 am

    This Is The History Of Top Exercise Bikes In 10 Milestones exercise bike promotions

  46. Keith on March 12, 2025 at 3:28 am

    It’s going to be ending of mine day, except before end I am
    reading this wonderful article to improve my knowledge.

    Also visit my blog post … https://tk88.nom.co/

  47. Miriam on March 12, 2025 at 3:53 am

    I got this site from my pal who shared with me on the topic of this site and now this time I am visiting this
    site and reading very informative articles or reviews at this time.

    Also visit my web site … sexy cars for guys (werehomenow.blogspot.com)

  48. Aidan on March 12, 2025 at 3:54 am

    How To Save Money On Buy Fake Driver’s License Online KöPa KöRkort Online

  49. Dean on March 12, 2025 at 4:07 am

    What Is Buy Category B1 Driving License? History Of Buy Category B1 Driving License Comprar carta de condução categoria B (http://Www.omageilblog.com)

← Older Comments
Newer Comments →

Submit a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top